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Clinical trials that are designed to help inform practice in the real world are called pragmatic trials. They are often characterized by their focus on practical aspects of study design that include the recruitment process and consent, adhering and the use of standard equipment.

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A pragmatic trial that uses different investigators and participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This type of heterogeneity, which is essential for pragmatic trials to be reliable and 프라그마틱 슈가러쉬 (browse around this site) reduce bias in results, is also necessary. However excessive heterogeneity could result in problems with the design of the trial.

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The aim of pragmatic trials is to simulate real-life situations and achieve maximum validity externally. They are usually commissioned by policy makers and practitioners to inform their decision making. They are also a good method of determining the causality between an intervention and its results. They should not, however be used to replace the need for explanation studies.

The pragmatism concept is controversial, and there are questions about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which confirm a physiological or clinical hypothesis and pragmatic trials, which guide the policy and practice of. They also suggested an approach to pragmatic trials, called PRECIS.2 This tool sought to define the features of a pragmatic trial that include recruitment, design and delivery of the intervention, and the follow-up.

There is a growing trend in the number of pragmatic trials that are published. A recent Medline search using the words pragmatic and naturalistic, 프라그마틱 무료체험 슬롯버프 which was restricted to randomised controlled trials (RCTs), returned 34 articles. These are highlighted in red on Figure 2. This is a sign that the health science community is becoming increasingly sensitized to the issue of pragmatism. It is important to keep in mind that the majority were conducted in primary-care settings.